Medical Administrative Assistant salary and cost of hiring in South Carolina
The median medical administrative assistant in South Carolina earned $40,170 a year in May 2025[1], 12.5% below the US median of $45,930. That puts South Carolina at #43 of 51 states for this job.
BLS occupation 43-6013. Data from the May 2025 release, checked 2026-10-15.
Salary range
| Range | 10th | Median | 90th | |
|---|---|---|---|---|
| South Carolina | $34,780 | $40,170 | $56,890 | |
| United States | $35,930 | $45,930 | $60,530 |
The middle half of medical administrative assistants in South Carolina earns $36,940–$46,690; the top tenth earns $56,890 or more, 1.6 times the bottom tenth.
What a hire really costs
Benefits and payroll taxes are 30.0% of total compensation in US private industry[2]. At the South Carolina median that makes about $57,386 a year before recruiting, equipment and office space. Benefit levels vary by employer, so treat this as an estimate.
We place executive assistants, customer support and e-commerce staff today; for medical administrative assistants we answer within one business day whether we can help. Enter the monthly pay you have in mind to compare it with a local hire. The fee field shows our standard fee[3]; Deel's contractor plan is the default payroll tool[4].
Pay by metro area in South Carolina
| Area | Median | 75th percentile | Jobs |
|---|---|---|---|
| Charleston-North Charleston, SC | $47,630 | 3,040 | |
| Hilton Head Island-Bluffton-Port Royal, SC | $47,110 | 740 | |
| Columbia, SC | $45,400 | 2,230 | |
| Spartanburg, SC | $47,020 | 780 | |
| Greenville-Anderson-Greer, SC | $46,310 | 3,090 | |
| Sumter, SC | $46,010 | 190 | |
| Myrtle Beach-Conway-North Myrtle Beach, SC | $44,760 | 1,070 | |
| Northwestern South Carolina nonmetropolitan area | $43,970 | 520 | |
| Northeastern South Carolina nonmetropolitan area | $45,240 | 470 | |
| Southern South Carolina nonmetropolitan area | $44,830 | 390 | |
| Florence, SC | $46,280 | 790 |
Charleston-North Charleston, SC pays the most ($44,640) and Florence, SC the least ($37,030): $7,610 a year apart for the same job.
What a medical administrative assistant does
A medical administrative assistant handles a clinic's front and back office: scheduling, insurance checks, referrals, patient messages and records.
Neighbours in the ranking
Questions
How much does a medical administrative assistant earn in South Carolina?
The median was $40,170 a year in the May 2025 BLS survey; the middle half earned $36,940 to $46,690.
What does it cost to employ a medical administrative assistant in South Carolina?
About $57,386 a year at the median wage once benefits are added, using the 30% benefits share of US private industry (June 2026).
Where in South Carolina do medical administrative assistants earn the most?
Charleston-North Charleston, SC, with a median of $44,640 a year.
Sources
- BLS OEWS May 2025, 43-6013: https://www.bls.gov/oes/current/oes436013.htm
- BLS Employer Costs for Employee Compensation, private industry, June 2026: https://www.bls.gov/news.release/ecec.nr0.htm
- Silkstaff pricing: https://silkstaff.com/#pricing
- Deel pricing, contractor management: https://www.deel.com/pricing/
How these pages are built: methodology and data sources. Last updated 2026-11-05.