Medical Administrative Assistant salary in Cape Girardeau, MO-IL

Pay in Cape Girardeau against Missouri and the US

The middle half of medical administrative assistants in Cape Girardeau earns $36,110–$46,410. Pay is tightly grouped: the top tenth starts at $48,930, only 1.4 times the bottom tenth, against 1.7 times across the US, so the going rate is easier to read. The mean ($40,750) is 9% over the median, so a group of high earners pulls the average up; price a typical hire from the median. From the 25th to the 75th percentile, the local range is only $10,300 wide, against $11,000 across Missouri and $12,010 nationally: employers in Cape Girardeau pay within a narrower band.

What to budget for a medical administrative assistant here

Pay climbs faster above the median than below it here: the 75th percentile is $9,050 over the median, the 25th only $1,250 under it. An offer at the 75th percentile adds about $11,677 a year in employer cost. These percentiles describe what people in the job earn locally, not experience levels, so place your offer by the tasks and seniority you need.

For scale, the US median of $45,930 falls between the median and the 75th percentile in Cape Girardeau, and the Missouri statewide median of $43,980 falls there too.

What a hire really costs in Cape Girardeau

Pay is only part of it. Benefits and payroll taxes other than paid leave are 22.5% of total compensation in US private industry², which adds about $10,846 to the $37,360 median and brings it to $48,206 a year. Recruiting, equipment and office space come on top. Benefit levels vary by employer, so treat this as an estimate.

We place executive assistants, customer support and e-commerce staff today; for medical administrative assistants we answer within one business day whether we can help. Enter the monthly pay you have in mind to compare it with a local hire. The fee field shows our standard fee³; Deel's contractor plan is the default payroll tool⁴.

Other roles in Cape Girardeau

Of the 14 roles we track in Cape Girardeau, this one ranks #13 by median pay, between administrative assistants ($37,480) and virtual receptionists ($34,750). Project Coordinator is the highest at $78,150.

Measured against the US median, medical administrative assistants rank #5 of the 14 roles we track in Cape Girardeau (-18.7%), between office managers (-15.6%) and recruiters (-20.1%). The typical role here is at -22.3%, so, measured against the US, medical administrative assistants cost more in Cape Girardeau than the area's general pay level would suggest. Medical administrative assistants hold 8.1% of the jobs in these 14 roles in Cape Girardeau, 4.5% across Missouri and 6.2% nationally. The job is a bigger part of the local workforce in these roles than it is nationally.

Other areas in Missouri

Across the 12 areas of Missouri with data for this job, the median runs from $36,810 in the Southeast Missouri nonmetro area to $45,620 in St. Louis, a gap of $8,810 a year. Of the 7 areas in Missouri with more medical administrative assistants than Cape Girardeau, 2 pay less: Springfield, MO ($37,150) and the Southeast Missouri nonmetro area ($36,810).

Cape Girardeau against other US metro areas

By number of jobs, Cape Girardeau is #401 of 514 US areas for this job. It is a small market, and its pay is in the bottom quarter of US areas. Outside Missouri, Clarksville and Gulfport-Biloxi pay just above Cape Girardeau and Roanoke and Lawton just below. All four are within $130 a year of the median in Cape Girardeau. Of the three markets with about as many medical administrative assistants, all three pay more.

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How these pages are built: methodology and data sources. Last updated 2026-11-13.