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Medical Administrative Assistant salary in Greenville-Anderson, SC

Greenville-Anderson is a lower-cost market for medical administrative assistants: the median of $39,410 a year1 is 1.9% below the South Carolina statewide median of $40,170, and 14.2% below the US median of $45,930. Among US areas it comes in at #338 of 516. With about 3,090 medical administrative assistants, 20% of the South Carolina total, no area in South Carolina employs more.

$3,284median pay per month in Greenville-Anderson
$4,238employer cost per month with benefits
$18.95median pay per hour
3,090people in this job in Greenville-Anderson

BLS occupation 43-6013, area Greenville-Anderson-Greer, SC. Data from the May 2025 release, checked 2026-10-15.

Pay in Greenville-Anderson against South Carolina and the US

Range10thMedian90th
Greenville-Anderson, SC$35,610$39,410$53,250
South Carolina$34,780$40,170$56,890
United States$35,930$45,930$60,530
10th to 90th percentilemiddle half (25th to 75th)median

The middle half of medical administrative assistants in Greenville-Anderson earns $37,460–$46,310. Pay is tightly grouped: the top tenth starts at $53,250, only 1.5 times the bottom tenth, against 1.7 times across the US, so the going rate is easier to read. From the 25th to the 75th percentile, the local range is only $8,850 wide, against $9,750 across South Carolina and $12,010 nationally: employers in Greenville-Anderson pay within a narrower band.

What to budget for a medical administrative assistant here

Point in the local rangePer yearPer monthPer hourEmployer cost per year
10th percentile$35,610$2,968$17.12$45,948
25th percentile$37,460$3,122$18.01$48,335
Median$39,410$3,284$18.95$50,852
75th percentile$46,310$3,859$22.26$59,755
90th percentile$53,250$4,438$25.60$68,710

Pay climbs faster above the median than below it here: the 75th percentile is $6,900 over the median, the 25th only $1,950 under it. An offer at the 75th percentile adds about $8,903 a year in employer cost. These percentiles describe what people in the job earn locally, not experience levels, so place your offer by the tasks and seniority you need.

For scale, the US median of $45,930 falls between the median and the 75th percentile in Greenville-Anderson, and the South Carolina statewide median of $40,170 falls there too.

What a hire really costs in Greenville-Anderson

Pay is only part of it. Benefits and payroll taxes other than paid leave are 22.5% of total compensation in US private industry2, which adds about $11,442 to the $39,410 median and brings it to $50,852 a year. Recruiting, equipment and office space come on top. Benefit levels vary by employer, so treat this as an estimate.

We place executive assistants, customer support and e-commerce staff today; for medical administrative assistants we answer within one business day whether we can help. Enter the monthly pay you have in mind to compare it with a local hire. The fee field shows our standard fee3; Deel's contractor plan is the default payroll tool4.

$50,852local hire, first year incl. benefits
$13,888remote hire, first year incl. fee
$36,964difference in year one
73%of the local cost saved

Other roles in Greenville-Anderson

Of the 17 roles we track in Greenville-Anderson, this one ranks #14 by median pay, between e-commerce order specialists ($43,930) and data entry specialists ($39,120). Project Coordinator is the highest at $94,780.

The 5 roles closest in pay. All 17 roles in Greenville-Anderson, SC
RoleMedianvs medical administrative assistantJobs
Administrative Assistant
$46,120
+17.0%4,870
E-commerce Order Specialist
$43,930
+11.5%170
Medical Administrative Assistant
$39,410
this role3,090
Data Entry Specialist
$39,120
-0.7%300
Customer Support Specialist
$39,010
-1.0%9,430

Measured against the US median, medical administrative assistants rank #16 of the 17 roles we track in Greenville-Anderson (-14.2%), between customer support specialists (-12.9%) and sales development representatives (-26.5%). The typical role here is at -8.1%, so, measured against the US, medical administrative assistants cost less in Greenville-Anderson than the area's general pay level would suggest. Medical administrative assistants hold 6.6% of the jobs in these 17 roles in Greenville-Anderson, 6.3% across South Carolina and 6.1% nationally. That is close to the national mix.

Other areas in South Carolina

Across the 11 areas of South Carolina with data for this job, the median runs from $37,030 in Florence to $44,640 in Charleston-North Charleston, a gap of $7,610 a year. No other area in South Carolina has as many medical administrative assistants, and 6 of the other 10 pay less.

AreaMedianvs Greenville-AndersonJobs
Hilton Head Island-Bluffton, SC
$41,600
+5.6%740
Columbia, SC
$40,160
+1.9%2,230
Spartanburg, SC
$40,050
+1.6%780
Greenville-Anderson, SC
$39,410
this area3,090
Sumter, SC
$39,380
-0.1%190
Myrtle Beach-Conway, SC
$38,950
-1.2%1,070
Northwestern South Carolina (Nonmetro)
$37,950
-3.7%520

Greenville-Anderson against other US metro areas

By number of jobs, Greenville-Anderson is #57 of 514 US areas for this job. It is one of the larger markets for this job, with pay near the middle of the US range. Outside South Carolina, Savannah and Orlando-Kissimmee pay just above Greenville-Anderson and Dubuque and Davenport-Moline just below. All four are within $140 a year of the median in Greenville-Anderson. Of the three markets with about as many medical administrative assistants, all three pay more.

Metro areaMedianvs Greenville-AndersonJobsClose in
Buffalo-Cheektowaga, NY
$45,960
+16.6%3,110jobs
North Port-Bradenton, FL
$45,490
+15.4%3,150jobs
Asheville, NC
$41,520
+5.4%3,000jobs
Orlando-Kissimmee, FL
$39,520
+0.3%13,050pay
Savannah, GA
$39,430
+0.1%1,480pay
Greenville-Anderson, SC
$39,410
this area3,090
Dubuque, IA
$39,340
-0.2%410pay
Davenport-Moline, IA-IL
$39,270
-0.4%1,150pay

Questions

How much does it cost to hire a medical administrative assistant in Greenville-Anderson, SC?

About $50,852 a year at the median, or $4,238 a month: $39,410 in pay plus about $11,442 in benefits and payroll taxes. Recruiting, equipment and office space are extra.

What do medical administrative assistants earn in Greenville-Anderson?

The median was $39,410 a year in the May 2025 BLS survey. The 10th percentile was $35,610, the 90th $53,250, and the middle half earned $37,460 to $46,310.

Is Greenville-Anderson cheaper than the rest of South Carolina for medical administrative assistants?

Yes, it costs less: a median of $39,410 against $40,170 statewide. The next area up in South Carolina is Spartanburg at $40,050, the next down Sumter at $39,380.

How many medical administrative assistants work in Greenville-Anderson?

BLS counts about 3,090 in the May 2025 survey. That is 20% of the South Carolina total of 15,630. No other area in South Carolina has as many.

Does a medical administrative assistant cost more than a data entry specialist in Greenville-Anderson?

Yes: $290 a year more at the median. The medians are $39,410 and $39,120.

Sources

4 sources, with links
  1. BLS OEWS May 2025, 43-6013: bls.gov
  2. BLS Employer Costs for Employee Compensation, private industry, June 2026: bls.gov
  3. Stafka pricing: stafka.com
  4. Deel pricing, contractor management: deel.com

How these pages are built: methodology and data sources. Last updated 2026-11-12.