Medical Administrative Assistant salary in Florence, SC

Pay in Florence against South Carolina and the US

Pay is more spread out here than nationally: the top tenth earns $61,330 or more, 2.0 times the bottom tenth, against 1.7 times across the US. Two offers for the same title can sit far apart. The middle half of medical administrative assistants in Florence earns $31,910–$46,280. The mean ($41,290) is 12% over the median, so a group of high earners pulls the average up; price a typical hire from the median. From the 25th to the 75th percentile, the local range is $14,370 wide, wider than in South Carolina as a whole ($9,750) and the US ($12,010), so what a medical administrative assistant earns in Florence depends more on the employer.

What to budget for a medical administrative assistant here

Pay climbs faster above the median than below it here: the 75th percentile is $9,250 over the median, the 25th only $5,120 under it. An offer at the 75th percentile adds about $11,935 a year in employer cost. These percentiles describe what people in the job earn locally, not experience levels, so place your offer by the tasks and seniority you need.

For scale, the US median of $45,930 falls between the median and the 75th percentile in Florence, and the South Carolina statewide median of $40,170 falls there too.

What a hire really costs in Florence

Pay is only part of it. Benefits and payroll taxes other than paid leave are 22.5% of total compensation in US private industry², which adds about $10,751 to the $37,030 median and brings it to $47,781 a year. Recruiting, equipment and office space come on top. Benefit levels vary by employer, so treat this as an estimate.

We place executive assistants, customer support and e-commerce staff today; for medical administrative assistants we answer within one business day whether we can help. Enter the monthly pay you have in mind to compare it with a local hire. The fee field shows our standard fee³; Deel's contractor plan is the default payroll tool⁴.

Other roles in Florence

Of the 14 roles we track in Florence, this one ranks #13 by median pay, between customer support specialists ($37,270) and virtual receptionists ($33,130). Project Coordinator is the highest at $87,400.

Measured against the US median, medical administrative assistants rank #10 of the 14 roles we track in Florence (-19.4%), between recruiters (-19.3%) and executive assistants (-22.1%). The typical role here is at -15.7%, so, measured against the US, medical administrative assistants cost less in Florence than the area's general pay level would suggest. Medical administrative assistants hold 9.8% of the jobs in these 14 roles in Florence, 6.3% across South Carolina and 6.2% nationally. The job is a bigger part of the local workforce in these roles than it is nationally.

Other areas in South Carolina

Across the 11 areas of South Carolina with data for this job, the median runs from $37,030 in Florence to $44,640 in Charleston-North Charleston, a gap of $7,610 a year. All 4 areas in South Carolina with more medical administrative assistants than Florence also pay more, among them Greenville-Anderson, SC ($39,410) and Charleston-North Charleston, SC ($44,640).

Florence against other US metro areas

By number of jobs, Florence is #209 of 514 US areas for this job. It is a mid-sized market, and its pay is in the bottom quarter of US areas. Outside South Carolina, Brownsville-Harlingen and Monroe pay just above Florence and Longview and Elizabethtown just below. All four are within $110 a year of the median in Florence. Of the three markets with about as many medical administrative assistants, all three pay more.

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Sources

How these pages are built: methodology and data sources. Last updated 2026-11-12.